Two Japanese scientists, one an established professor (right) and the other his last graduate student (left), lay the groundwork for research at City of Hope.
Riojun Kinosita, M.D., Ph.D., was an internationally recognized pathologist/oncologist who brought with him young Susumu Ohno, D.V.M., who in his long career at City of Hope became one of the world's most renowned geneticists and evolutionary biologists.
Susumu Ohno (1928-2000)
Drs. Susumu Ohno and Ernest Beutler. Dr. Ohno was holding the Time January 4, 1963, in which their work was highlighted; on page 45, under Medicine HEREDITY, “Research Makes it Official: Women Are Genetic Mosaics”
Dr. and Mrs Ohno in 1954
Dr. and Mrs. Susumu Ohno with their first son Azusa (1955)
The first research group photo taken in front of the Warner Memorial Building (August, 1952), including Professor Riojun Kinosita and Susumu Ohno, D. V. M. (later Ph. D.).
Early members of City of Hope medical and research groups. Standing in back, left to right: Joe Holden, x, x, William Kaplan, x, Fred Preuss, x, Susumu Ohno, Riojun Kinosita, x, Alfred Goldman, x, Howard Bierman, x, x, Eugene Roberts, George Rouser, x, x. (x = unidentified)
Division of Biology in 1965. (Left to Right) Marcel Baluda, Susumu Ohno, Alfred Knudson, Robert Seecof, William Kaplan, and Jesse Sisken, in front of Lippman-Graff Building.
To Dr. Wolfwith complementsSusumu Ohno
To Dr. and Mrs. Eugene Robertswith complementsJune 9, 1981Susumu OhnoThis poem admiring a fine horse by Du Fu* was depicted.
*Du Fu, 杜甫 in Chinese (712–770) was a prominent Chinese poet of the Tang Dynasty. Along with Li Bai (Li Bo), he is frequently called the greatest of the Chinese poets.
X chromosome inactivation
The seminal work of Ohno and Beutler was highlighted in the January 4, 1963 issue of Time magazine, under Medicine HEREDITY, “Research Makes it Official: Women Are Genetic Mosaics.”Dr. Ernest Beutler became Chairman of the Department of Medicine at City of Hope in 1959, where he met a new colleague who became a lifelong friend. Ohno published that the two X-chromosomes of mammals were different: one appeared like the autosomes; the other was condensed and heterochromatic. Beutler soon determined that random X chromosome inactivation causes tissue mosaicism in female mammals in that each somatic cell expresses one (but not both) of the alleles of X-linked. Photo:Drs. Ohno (left) and Beutler (right)
Dr. Susumu Ohno looking at his famous book "Evolution bu Gene Duplication" October 1970
Composed by Susumu OhnoEample 1：Phosphoglycerate kinase
Composed by Susumu Ohno Eample 2：Human Blood Clotting VIII
Dr. Ohno enjoying a conversation with a miniature horse, circa 1995. Miniature horses were his favorites.
Dr. Ohno surrounded by his friends and collaborators, Dr. Sergei Rodin and Dr. Gerald Holmquist. City of Hope campus, late 90s.
Dr. Ohno on campus, City of Hope, circa 1997
Dr. Ohno and Queen MargaretReceived the Inaugural Queen Margaret Prize from the Royal Danish Academy of Arts and Sciences in 1998
Left to Right: Mrs. and Dr. Ernest Beutler, Dr. and Mrs. Akira Yoshida, Mrs. and Dr. Susumu Ohno, and Mrs. Charles Todd at the retirement party for Dr. Akira Yoshida in 1998. Courtesy of Michiko Yoshida
Susumu Ohno Memorial Lecture was inaugurated in 2014
Dedication of an Oak Tree in 12014 in celebration of Dr. Ohno’s legacyMarcia Miller, Midori Ohno, Yoko Yamaguchi, Andrei Rodin, Eugene Roberts & Arthur Riggs
Drs. Susumu Ohno (right) and Yoko Fujita-Yamaguchi (left) at a party on January 8, 1982, celebrating the Department of Molecular Genetics opening headed by Dr. Ikeiichi itakura.
The portrait of Dr. Susumu Ohno, the original painting of which was donated by Midori Ohno to Dr. Ohno’s alma mater in Japan. It was painted circa mid-50s by a Hungarian artist, John Bernat, who was hospitalized at City of Hope in 1948 after being diagnosed with lung cancer. Bernat mastered the technique of creating anatomical drawings and soon became City of Hope's medical illustrator.
He opened a studio in what is now the Visitor Center. In the mid-1950s, he painted nine-foot-tall
images of David and Moses on the exterior of the House of Hope - murals restored in 2012 with the composition’s reopening as the La Kretz House of Hope. Bernat died in 1964.
More than a muralist: Artist in residence made his visual mark
By Susan Douglass Yates
City News, Winter 2013, page 36